From I-91 North (Holyoke, Mass Pike, Springfield, or Bradley Airport in Connecticut):

EXIT 19 (Northampton & Amherst):  At end of ramp (intersection of Rt 9 & Damon Rd), go straight through the lights onto Damon Rd.  At next set of lights (intersection of Damon Rd and Rts 5&10), continue straight through lights onto Bridge Rd (Webber & Grinnell Insurance on far right corner, D'Angelo's on far left).   At next light (intersection of Jackson St and Bridge Rd), take a left onto Jackson St.  At end of Jackson St (1/2 mile), take a right onto Prospect St.  At next set of lights (Cooley Dickinson Hospital is in front of you), take a slight right onto Rt 9, Locust St.  Go past the low buildings on your right (Anton Corliss Cleaners, video store), 2 other medical buildings.  The large two-story light green building is 61 Locust St (across from the hospital and Smith Vocational School).  We are on the second floor.

From I-91 South (Vermont, Greenfield):

EXIT 20 (Northampton):  At end of ramp onto Rt 5&10 to the lights (intersection of Bridge Rd and Rts 5&10).  Woodward & Grinnell Insurance is on your right.  Take a right onto Bridge Rd.  At next light (intersection of Jackson St and Bridge Rd), take a left onto Jackson St.  At end of Jackson St (1/2 mile), take a right onto Prospect St.  At next set of lights (Cooley Dickinson Hospital is in front of you), take a slight right onto Rt 9, Locust St.  Go past the low buildings on your right (Anton Corliss Cleaners, video store), 2 other medical buildings.  The large two-story light green building is 61 Locust St (across from the hospital and Smith Vocational School).  We are on the second floor.